The biometric parameters of aniso-astigmatism and its risk factor in Chinese preschool children: the Nanjing eye study

Abstract Backgrounds Aniso-astigmatism may hinder normal visual development in preschool children. Knowing its prevalence, biometric parameters and risk factors is fundamental to children eye care. The purpose of this study was determine the components aniso-astigmatism associated maternal Chinese Methods In population-based, prospective cohort Nanjing Eye Study, were measured for noncycloplegic refractive error using an autorefractor optical low-coherent reflectometry. difference total astigmatism (TA) between both eyes calculated cylinder power (non-vectorial aniso-TA defined as ?1.00 Dioptre Cylinder [DC] eyes) by vector analysis (vectorial a ?0.5 J 0 or 45 which equivalent 1.00 DC). prevalence presented. Interocular compared with vs. without group. addition, determined multivariate logistic regression model. Results Of 1131 (66.90 ± 3.38 months, 53.31% male), non-vectorial 1.95% (95% Confidence Interval (CI) = 1.14–2.75%), while vectorial twice common aniso-TA, neither varying sex age. With more asymmetric axial length corneal curvature radius than eyes. model, 5-min Apgar score less 7 significantly higher aniso-TA: Odds Ratio (OR) 6.42, 95%CI 2.63–15.69, P < 0.001; OR 4.99, 1.41–17.68, 0.01). Being twin triple aniso-CA (OR 2.43, 1.05–5.60, 0.04). Pre-term delivery 2.60, 1.09–6.15, 0.03) post-term 3.61, 1.31–9.96, 0.01) aniso-CA. Conclusions Both asymmetry correlated aniso-TA. Children likely have triple, pre-term